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It was found that naltrexone and bupropion combined, which might be marketed in the foreseeable future as Contrave, provide better weight loss results than dieting and exercise alone.

Using two separate drugs to shed weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it one should err to the side of caution and permit the FDA do its job and demand some research be done so your public knows the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say everything to keep people on his or her medications.

Researchers found out that participants using this drug to get a year, dropped excess weight within a month and have kept the body weight off throughout the 56 weeks in the study. Contrave is really a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which can be made up of more than one active ingredient, that might make them far better and safer.

Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills has become popular may be the fact that as of right now there aren't long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA.

Seizures certainly are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug may also raise hypertension and heartbeat, and shouldn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high blood pressure, in addition to by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients towards the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.


Most of the combinations which might be used to enhance weight loss involve an amphetamine and an antidepressant. Phentermine and Prozac are a popular combination that have been around for quite a while, and even though it has been around no one wants to truly combine both the and try to get FDA approval to advertise it as a fat loss pill. Right there should raise some warning flag if the greedy pharmaceutical companies don't want to be involved in combining medications and selling them something has to be wrong using the combination. In fairness there exists one weight loss combination pill which is in front of the FDA now Contrave?which couples naltrexone, utilized to treat alcohol and abusing drugs, with all the antidepressant bupropion (Wellbutrin, Zyban) it is often given the go ahead to move forward by an FDA advisory committee, but since yet will not be approved.